Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563705 | 0.83 | MAOA (0.33) | MAOAKDM4ENPC1FLT3GSK3B | |
| SCHEMBL7571442 | 0.81 | MAOA (0.31) | MAOA | |
| SCHEMBL7571161 | 0.80 | MAOA (0.31) | MAOA | |
| SCHEMBL8676204 | 0.79 | GABRG2 (0.33) | MAOAKDM4ENPC1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL7571445 | 0.78 | MAOA (0.32) | MAOAKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL7564378 | 0.72 | MAOA (0.37) | MAOAKDM4ENPC1GABRG2GABRB3 | |
| SCHEMBL7564070 | 0.69 | GABRG2 (0.32) | MAOAGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL8675389 | 0.68 | ADRA1A (0.33) | KDM4ENPC1LMNACYP1A2POLB | |
| Hydrochloric Acid SCHEMBL7564075 | 0.68 | GABRG2 (0.32) | MAOAKDM4ENPC1GABRG2GABRB3 | |
| SCHEMBL5952691 | 0.67 | MAOA (0.33) | MAOAKDM4ENPC1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | claimed |