Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676387 | 0.88 | PTGER1 (0.62) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8677570 | 0.86 | PTGER1 (0.57) | PTGER1MRGPRX4TDP1 | |
| SCHEMBL8675525 | 0.85 | PTGER1 (0.61) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8319795 | 0.81 | PTGER1 (0.78) | PTGER1PTGER4PTGER3PTGER2SLC1A5 | |
| SCHEMBL8676742 | 0.81 | PTGER1 (0.56) | PTGER1PTGER4PTGER3PTGER2SLC1A5 | |
| SCHEMBL8678347 | 0.80 | HTR1A (0.62) | PTGER1PTGER4PTGER3PTGER2SLC1A5 | |
| SCHEMBL8677652 | 0.80 | PTGER1 (0.49) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8675455 | 0.79 | ESR1 (0.52) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8676066 | 0.79 | ESR1 (0.52) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8677246 | 0.79 | ABCB1 (0.60) | PTGER1PTGER4PTGER3PTGER2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |