Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676387 | 0.89 | PTGER1 (0.62) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676634 | 0.88 | MTNR1B (0.57) | ABCB1MTNR1BMTNR1AHTR1ADRD2 | |
| SCHEMBL8675525 | 0.86 | PTGER1 (0.61) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7774976 | 0.81 | PTGER1 (0.59) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8321843 | 0.81 | PTGER1 (0.81) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8677032 | 0.81 | ABCB1 (0.63) | ABCB1MTNR1BSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL8677245 | 0.80 | ABCB1 (0.64) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8678180 | 0.79 | HTR1A (0.56) | NPC1RAB9ASMN1; SMN2MAPTHTR1A | |
| SCHEMBL8676744 | 0.79 | PTGER1 (0.50) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8678347 | 0.79 | HTR1A (0.62) | ABCB1PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |