Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661911 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPK1VNN1RAB9ALMNA | |
| SCHEMBL21100152 | 0.85 | IAPP (0.46) | ALDH1A1RAB9A | |
| SCHEMBL8388641 | 0.85 | RIPK1 (0.48) | RIPK1VNN1CXCL8MEN1KMT2A | |
| SCHEMBL8677157 | 0.85 | VNN1 (0.50) | ALDH1A1RIPK1MAPK1VNN1RAB9A | |
| SCHEMBL28005176 | 0.83 | IAPP (0.47) | ALDH1A1RIPK1MAPK1CXCL8 | |
| SCHEMBL1538027 | 0.82 | VNN1 (0.48) | ALDH1A1RIPK1MAPK1VNN1RAB9A | |
| Bicarbonate SCHEMBL28309385 | 0.81 | ALDH1A1 (0.51) | ALDH1A1RIPK1MAPK1RAB9ALMNA | |
| SCHEMBL29210932 | 0.81 | GABRA1 (0.44) | ALDH1A1RAB9A | |
| SCHEMBL2206253 | 0.81 | ALDH1A1 (0.48) | ALDH1A1RIPK1MAPK1VNN1RAB9A | |
| SCHEMBL27524951 | 0.81 | TDP1 (0.50) | ALDH1A1RIPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326919-B | Phenyl butanone of 5 nitro of compound 2 hydroxyl, 3 fluorine 1 and preparation method thereof and agricultural biological activity | 青岛农业大学 | 2018-01-02 | — | — | CN | claimed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-114874061-A | Preparation method of prasugrel intermediate and analogue thereof | 中国人民解放军海军军医大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-104326919-B | Phenyl butanone of 5 nitro of compound 2 hydroxyl, 3 fluorine 1 and preparation method thereof and agricultural biological activity | 青岛农业大学 | 2018-01-02 | — | — | CN | disclosed |
| US-8389541-B2 | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2013-03-05 | — | — | US | disclosed |
| CN-1107502-C | Preparation method for medicinal composition containing hydrogenated pyridine derivative as active components | SANKYO CO (JP) | 2003-05-07 | — | — | CN | disclosed |
| CN-1217186-A | Preparation method for medicinal composition containing hydrogenated pyridine derivative as active components | SANKYO CO (JP) | 1999-05-26 | — | — | CN | disclosed |
| CN-1041730-C | Process for preparing hydrogenated pyridine derivatives | SANKYO CO (JP) | 1999-01-20 | — | — | CN | disclosed |
| EP-0542411-B1 | TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION | SANKYO CO (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5436242-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5288726-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | UBE INDUSTRIES LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| CN-1074446-A | Hydroxypyridine Derivatives | SANKYO CO (JP) | 1993-07-21 | — | — | CN | disclosed |
| EP-0542411-A2 | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | ALDH1A1 982/4885RIPK1 4224/4885MAPK1 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.