Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SYK | P43405 | 3/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5904242 | 0.92 | KMT2A (0.53) | ESR2KMT2ASYKAURKBINCENP | |
| Dimethylamine SCHEMBL5358041 | 0.89 | KMT2A (0.50) | KMT2ASYKAURKBINCENPMAPT | |
| Dimethylamine SCHEMBL9695311 | 0.87 | KMT2A (0.49) | KMT2ASYKAURKBINCENPMAPT | |
| SCHEMBL8675465 | 0.84 | MAPT (0.59) | ESR2NOX1KMT2AMAPTTP53 | |
| SCHEMBL4037256 | 0.83 | ALDH1A1 (0.57) | ESR2NOX1SYKAURKBINCENP | |
| SCHEMBL8678444 | 0.81 | NPSR1 (0.55) | KMT2ASYKAURKBINCENPMAPT | |
| SCHEMBL8811479 | 0.80 | ESR2 (0.51) | ESR2NOX1KMT2AMAPTTP53 | |
| SCHEMBL8680387 | 0.79 | MAPT (0.56) | ESR2NOX1KMT2AMAPTTP53 | |
| SCHEMBL8677193 | 0.78 | MAPT (0.52) | ESR2NOX1KMT2AMAPTTP53 | |
| SCHEMBL8809606 | 0.78 | ESR1 (0.48) | ESR2KMT2AMAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750708-A | Pyridine compounds intermediates processes compositions and methods | ELI LILLY AND COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5672609-A | POSTMENOPAUSAL SYNDROME; ANTILIPEMIC AND -CARCINOGENIC AGENTS; OSTEOPOROSIS; CARDIOTONIC AGENTS; RESTENOSIS; SIDE EFFECT REDUCTION COMPARED TO ESTROGEN | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| WO-1997004778-A1 | PYRIDINE COMPOUNDS, INTERMEDIATES, PROCESSES, COMPOSITIONS, AND METHODS | ELI LILLY AND COMPANY (US) | 1997-02-13 | — | — | WO | disclosed |