SCHEMBL8678477

SCHEMBL8678477

C=CCCC1=Cc2ccccc2[CH]1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1135141 0.80 GAA (0.31)
SCHEMBL2956508 0.79 GABRA1 (0.31)
SCHEMBL6896931 0.76
SCHEMBL7566437 0.74 LIPG (0.31)
SCHEMBL2958230 0.72 TDP1 (0.41) TDP1
SCHEMBL2965395 0.72
SCHEMBL27638220 0.71 KDM4E (0.31) ALDH1A1HPGD
SCHEMBL27619050 0.71 KDM4E (0.31) ALDH1A1HPGD
SCHEMBL2948401 0.71 HSPA5 (0.31)
SCHEMBL2961676 0.69 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770663-A HOMO OR COPOLYMERIZING UNSATURATED MONOMER SELECTED FROM ALPHA-OLEFIN IN PRESENCE OF METALLOCENE CATALYST AND A ORGANOMETALLIC COMPOUND OF 1A, 2A AND 3B AS COCATALYST PHILLIPS PETROLEUM COMPANY (US) 1998-06-23 US claimed
US-5770663-A HOMO OR COPOLYMERIZING UNSATURATED MONOMER SELECTED FROM ALPHA-OLEFIN IN PRESENCE OF METALLOCENE CATALYST AND A ORGANOMETALLIC COMPOUND OF 1A, 2A AND 3B AS COCATALYST PHILLIPS PETROLEUM COMPANY (US) 1998-06-23 US disclosed
US-5654454-A REDUCING UNSATURATED SUBSTITUENTS; USED FOR ADDITION POLYMERIZATION OF OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1997-08-05 US disclosed
EP-0745607-A2 Metallocene preparation and use PHILLIPS PETROLEUM COMPANY (US) 1996-12-04 EP disclosed