Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678477 | 0.79 | USP2 (0.30) | — | |
| SCHEMBL7040493 | 0.79 | MAPT (0.33) | GABRA1GABRB2 | |
| SCHEMBL4650535 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2 | |
| SCHEMBL6525255 | 0.76 | XDH (0.44) | GABRA1GABRB2 | |
| SCHEMBL7562247 | 0.76 | XDH (0.44) | GABRA1GABRB2 | |
| SCHEMBL2948401 | 0.74 | HSPA5 (0.31) | — | |
| SCHEMBL1135141 | 0.74 | GAA (0.31) | — | |
| SCHEMBL4653119 | 0.72 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL8427622 | 0.72 | IDO1 (0.40) | — | |
| SCHEMBL2967523 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059370-B1 | Reduced shrinkage in metallocene isotactic polypropylene fibers | TOTAL PETROCHEMICALS RES FELUY (BE) | 2010-09-01 | — | — | EP | claimed |
| EP-1188763-B1 | Metallocenes and their use in olefin polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2005-03-09 | — | — | EP | claimed |
| EP-1188763-A2 | Metallocenes and their use in olefin polymerisation | Basell Polyolefine GmbH (DE) | 2002-03-20 | — | — | EP | claimed |
| US-5693730-A | METALLOCENES HAVING MORE THAN ONE CENTRAL ATOM AND A SPECIAL BRIDGE STRUCTURE FOR PREPARING ISOTACTIC, HIGH-MOLECULAR-WEIGHT POLYMERS HAVING GOOD GRAIN MORPHOLOGY; PROPYLENE HOMO- AND COPOLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | claimed |
| EP-0906932-B1 | Film and stretch packaging film | DENKI KAGAKU KOGYO KK (JP) | 2008-07-02 | — | — | EP | disclosed |
| EP-1279754-B1 | Metallocene catalyzed propylene-alpha-olefin random copolymer melt spun fiber | TOTAL PETROCHEMICALS RES FELUY (BE) | 2006-08-30 | — | — | EP | disclosed |
| US-7081543-B2 | Bridged biscyclopentadienyl ligands and method of preparation | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-07-25 | — | — | US | disclosed |
| US-20050250956-A1 | Bridged biscyclopentadienyl ligands and method of preparation | RIX FRANCIS C | 2005-11-10 | — | — | US | disclosed |
| US-6960676-B2 | Method of preparing group 14 bridged biscyclopentadienyl ligands | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-11-01 | — | — | US | disclosed |
| EP-1188763-B1 | Metallocenes and their use in olefin polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2005-03-09 | — | — | EP | disclosed |
| EP-1263764-B1 | METHOD OF PREPARING GROUP 14 BRIDGED BISCYCLOPENTADIENYL LIGANDS | EXXONMOBIL CHEM PATENTS INC (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030220190-A1 | Method of preparing group 14 bridged biscyclopentadienyl ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-11-27 | — | — | US | disclosed |
| US-5543373-A | OLEFIN POLYMERIZATION CATALYST | HOECHST AG (DE) | 1996-08-06 | — | — | US | disclosed |
| US-5532396-A | HAS TWO INDENYL LIGANDS WITH DIFFERENT SUBSTITUTION PATTERNS ON THE SIX-MEMBERED RINGS. LIGANDS ARE JOINED BY DIVALENT GROUP CONNECTING FIVE-MEMBERED RINGS. METAL IS FROM GROUP /IVB/, /VB/ OR /VIB/. OLEFIN POLYMERIZATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |
| CN-1109061-A | Metallocenic compound | HOECHST AG (DE) | 1995-09-27 | — | — | CN | disclosed |
| CN-1107854-A | Metalocenes compound | HOECHST AG (DE) | 1995-09-06 | — | — | CN | disclosed |
| CN-1107162-A | Metallocen method for preparation of same and application of same as catalyst | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| EP-0659756-A1 | Metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-28 | — | — | EP | disclosed |
| EP-0659757-A1 | Metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-28 | — | — | EP | disclosed |
| EP-0654476-A1 | Metallocenes, their preparation and use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250956-A1 | Bridged biscyclopentadienyl ligands and method of preparation | FDPS, PPIP5K2, DBF4 | GABRA1 3282/4885GABRB2 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.