SCHEMBL86786

SCHEMBL86786

C=CC(=O)Oc1ccc2c(c1)c(=O)c1ccccc1n2C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.52
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
KDM4E B2RXH2 4/20 0.48
HTT P42858 4/20 0.48
HSD17B10 Q99714 3/20 0.48
MAPT P10636 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
ATM Q13315 1/20 0.46
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
HCRTR1 O43613 2/20 0.43
KDM1A O60341 1/20 0.43
PTGS2 P35354 2/20 0.43
POLB P06746 2/20 0.42
NR2F2 P24468 1/20 0.42
CYP2C19 P33261 2/20 0.42
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6152266 0.79 L3MBTL1 (0.76) L3MBTL1MEN1KMT2AKDM4EHTT
SCHEMBL29037955 0.76 KDM4E (0.52) L3MBTL1MEN1KMT2AKDM4EHTT
SCHEMBL6151617 0.76 L3MBTL1 (0.58) L3MBTL1MEN1KMT2AKDM4EHTT
SCHEMBL8086565 0.75 L3MBTL1 (0.56) L3MBTL1MEN1KMT2AKDM4EHTT
SCHEMBL6151586 0.75 L3MBTL1 (0.56) L3MBTL1MEN1KMT2AKDM4EHTT
SCHEMBL16181632 0.75 PTPN1 (0.44) L3MBTL1MEN1KMT2AKDM4EHTT
SCHEMBL26622360 0.74 KMT2A (0.41) MEN1KMT2AKDM4EHSD17B10MAPT
SCHEMBL13609811 0.73 KDM4E (0.57) L3MBTL1MEN1KMT2AKDM4EHTT
SCHEMBL85778 0.73 MAPT (0.61) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL30998139 0.73 MAPT (0.61) L3MBTL1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 L3MBTL1 2764/4885MEN1 4036/4885KMT2A 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.