Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984129 | 0.84 | LMNA (0.33) | LMNA | |
| SCHEMBL3686958 | 0.84 | LMNA (0.33) | LMNA | |
| SCHEMBL8679362 | 0.80 | LMNA (0.32) | LMNA | |
| SCHEMBL1413774 | 0.80 | LMNA (0.32) | LMNA | |
| SCHEMBL1898494 | 0.77 | LMNA (0.30) | LMNA | |
| SCHEMBL9123202 | 0.77 | LMNA (0.37) | LMNA | |
| SCHEMBL379028 | 0.75 | LMNA (0.33) | LMNA | |
| SCHEMBL9101338 | 0.75 | — | — | |
| SCHEMBL9062561 | 0.74 | — | — | |
| SCHEMBL820991 | 0.74 | ALDH1A1 (0.30) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493412-A1 | METHOD OF DISSOLVING CHOLESTEROL-RICH CALCULI WITH SHORT CHAIN HALOGENATED ORGANIC SOLVENTS AND COSOLVENTS | BAXTER INTERNATIONAL INC. (US) | 1992-07-08 | — | — | EP | claimed |
| WO-1991003146-A2 | METHOD OF DISSOLVING CHOLESTEROL-RICH CALCULI WITH SHORT CHAIN HALOGENATED ORGANIC SOLVENTS AND COSOLVENTS | BAXTER INTERNATIONAL INC. (US) | 1991-03-21 | — | — | WO | claimed |