Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068458 | 0.82 | PLK1 (0.50) | SMN1; SMN2ALDH1A1PLK1LPLLIPG | |
| SCHEMBL8679873 | 0.79 | RARB (0.53) | ALDH1A1PLK1TP53LMNA | |
| SCHEMBL11871530 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1PLK1LPLLIPG | |
| SCHEMBL2257616 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1PLK1LPLLIPG | |
| SCHEMBL9341487 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1PLK1LPLLIPG | |
| SCHEMBL4828364 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1PLK1LPLLIPG | |
| SCHEMBL7224266 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1PLK1LPLLIPG | |
| SCHEMBL526436 | 0.76 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1PLK1LPLLIPG | |
| SCHEMBL11198091 | 0.76 | FAAH (0.44) | SMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL10937018 | 0.74 | CNR2 (0.44) | SMN1; SMN2GAATP53CYP2A6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037052-A1 | PREPARATION OF ARYL BROMOARYL KETONES AND CARBOXYLIC DERIVATIVES THEREOF | ALBEMARLE CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |
| US-4232038-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |