Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.46 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675277 | 0.83 | PTGER1 (0.52) | PTGER1CYP1A2CCR5HTTALDH1A1 | |
| SCHEMBL8675246 | 0.81 | LRRK2 (0.44) | PTGER1CYP1A2CCR5HTTALDH1A1 | |
| SCHEMBL8321883 | 0.80 | PTGER1 (0.47) | PTGER1CYP1A2CCR5HTTALDH1A1 | |
| SCHEMBL8679053 | 0.79 | PTGER1 (0.51) | PTGER1CYP1A2CCR5HTTALDH1A1 | |
| SCHEMBL4767265 | 0.76 | USP28 (0.59) | PTGER1CYP1A2CCR5HTTALDH1A1 | |
| SCHEMBL8406943 | 0.75 | HTR1A (0.65) | PTGER1CCR5HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8680267 | 0.75 | LRRK2 (0.49) | PTGER1CCR5HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL16294058 | 0.75 | PTGER1 (0.64) | PTGER1CYP1A2CCR5HTTALDH1A1 | |
| SCHEMBL8408122 | 0.73 | PTGER1 (0.62) | PTGER1CYP1A2CCR5HTTUSP28 | |
| SCHEMBL16294248 | 0.73 | USP28 (0.69) | PTGER1CYP1A2CCR5HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |