Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676667 | 0.99 | NPSR1 (0.55) | NPSR1MAPTALDH1A1LMNAHTT | |
| SCHEMBL8676788 | 0.93 | MAPT (0.50) | NPSR1MAPTALDH1A1LMNAHTT | |
| SCHEMBL10991494 | 0.88 | KDM4E (0.58) | NPSR1MAPTALDH1A1LMNAENPP3 | |
| SCHEMBL10976797 | 0.88 | KDM4E (0.58) | NPSR1MAPTALDH1A1LMNAENPP3 | |
| SCHEMBL8678444 | 0.86 | NPSR1 (0.55) | NPSR1MAPTALDH1A1LMNAHTT | |
| SCHEMBL8680387 | 0.85 | MAPT (0.56) | NPSR1MAPTALDH1A1LMNAACACA | |
| SCHEMBL8675465 | 0.80 | MAPT (0.59) | MAPTALDH1A1HTTMAPK1KDM4E | |
| SCHEMBL8809238 | 0.78 | LTA4H (0.58) | — | |
| SCHEMBL178694 | 0.78 | XDH (0.54) | NPSR1MAPTALDH1A1LMNAHTT | |
| SCHEMBL19091938 | 0.76 | GSTP1 (0.63) | GSTP1NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750708-A | Pyridine compounds intermediates processes compositions and methods | ELI LILLY AND COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5672609-A | POSTMENOPAUSAL SYNDROME; ANTILIPEMIC AND -CARCINOGENIC AGENTS; OSTEOPOROSIS; CARDIOTONIC AGENTS; RESTENOSIS; SIDE EFFECT REDUCTION COMPARED TO ESTROGEN | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| WO-1997004778-A1 | PYRIDINE COMPOUNDS, INTERMEDIATES, PROCESSES, COMPOSITIONS, AND METHODS | ELI LILLY AND COMPANY (US) | 1997-02-13 | — | — | WO | disclosed |