Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573271 | 0.89 | SMN1; SMN2 (0.55) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL8680301 | 0.89 | MAPT (0.53) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL29473569 | 0.89 | MAPT (0.50) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL13326515 | 0.89 | MAPT (0.50) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL976219 | 0.89 | MAPT (0.50) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL30612732 | 0.89 | MAPT (0.50) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL8680089 | 0.88 | MAPT (0.52) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL8680948 | 0.88 | MAPT (0.52) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL13889699 | 0.88 | MAPT (0.57) | MAPTLMNATDP1GAANPSR1 | |
| SCHEMBL8680104 | 0.88 | MAPT (0.52) | MAPTLMNATDP1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759729-A | A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY | XEROX CORPORATION (US) | 1998-06-02 | — | — | US | claimed |
| US-20170186514-A1 | STRAIN GAUGE POLYMER COMPRISING PHOTOCHROMIC COLORANT | XEROX CORPORATION | 2017-06-29 | — | — | US | disclosed |
| US-20110287549-A1 | TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | FRESHPOINT HOLDINGS SA (CH) | 2011-11-24 | — | — | US | disclosed |
| US-20110092364-A1 | OLIGOMERIC SPIROPYRANS FOR ERASABLE MEDIUM APPLICATIONS | XEROX CORPORATION (US) | 2011-04-21 | — | — | US | disclosed |
| US-5759729-A | A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY | XEROX CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| US-5710420-A | Method for embedding and recovering machine-readable information | XEROX CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5633109-A | Ink compositions with liposomes containing photochromic compounds | XEROX CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5593486-A | Photochromic hot melt ink compositions | XEROX CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| US-5551973-A | LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE | XEROX CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287549-A1 | TIME TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | TPI1, TTI1, TST | MAPT 2384/4885LMNA 1341/4885TDP1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.