Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461253 | 0.78 | MAPT (0.64) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL9485928 | 0.78 | HCRTR1 (0.52) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL9485199 | 0.76 | HCRTR1 (0.50) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL8684069 | 0.75 | RAB9A (0.46) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| Oxalic Acid SCHEMBL9484406 | 0.75 | HCRTR1 (0.49) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL9798916 | 0.73 | TDP1 (0.58) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL8681986 | 0.72 | KDM4E (0.60) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL6386416 | 0.71 | SMN1; SMN2 (0.58) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL11749690 | 0.71 | HCRTR1 (0.58) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL9798847 | 0.71 | GAA (0.64) | ALDH1A1MAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760028-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |