Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682718 | 0.86 | MAPK1 (0.44) | MAPK1MAPK3 | |
| SCHEMBL8682336 | 0.80 | PTGIR (0.46) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8682497 | 0.80 | KDM4E (0.39) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8684065 | 0.76 | RAB9A (0.47) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL9485928 | 0.76 | HCRTR1 (0.52) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8682283 | 0.76 | KDM4E (0.40) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8682632 | 0.75 | ALDH1A1 (0.56) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9485199 | 0.74 | HCRTR1 (0.50) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8683594 | 0.73 | JAK2 (0.43) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| Oxalic Acid SCHEMBL9484406 | 0.73 | HCRTR1 (0.49) | RAB9ANPC1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760028-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |