Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666857 | 0.89 | KMT2A (0.38) | MAPTRAB9AMMP2ALDH1A1MMP9 | |
| SCHEMBL8871034 | 0.89 | KMT2A (0.38) | MAPTRAB9AMMP2ALDH1A1MMP9 | |
| Hydrochloric Acid SCHEMBL8666991 | 0.88 | KMT2A (0.37) | MAPTRAB9AALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8685324 | 0.86 | L3MBTL1 (0.38) | MAPTCA2KMT2AL3MBTL1MEN1 | |
| SCHEMBL8689402 | 0.86 | MEN1 (0.35) | MAPTMMP2ALDH1A1HTTMMP9 | |
| Hydrochloric Acid SCHEMBL8689708 | 0.85 | MEN1 (0.35) | MAPTMMP2ALDH1A1HTTMMP9 | |
| SCHEMBL8686069 | 0.83 | RAB9A (0.38) | MAPTNPC1RAB9ACASP3SENP8 | |
| SCHEMBL8684526 | 0.81 | CYP2C19 (0.43) | MAPTSMN1; SMN2GAAHTTKMT2A | |
| SCHEMBL8684306 | 0.81 | MEN1 (0.37) | MAPTNPC1RAB9ASENP8SENP7 | |
| SCHEMBL8683694 | 0.78 | KMT2A (0.41) | MAPTRAB9AALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716936-A | Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders | RHONE-POULENC RORER S.A. (FR) | 1998-02-10 | — | — | US | disclosed |