Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | UBE2I | P63279 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670311 | 0.92 | KDM4E (0.35) | MEN1KMT2ACYP3A4CYP2C9HTR6 | |
| SCHEMBL8871034 | 0.89 | KMT2A (0.38) | MEN1KMT2ACYP3A4CYP2C9KAT6A | |
| SCHEMBL8666857 | 0.89 | KMT2A (0.38) | MEN1KMT2ACYP3A4CYP2C9KAT6A | |
| Hydrochloric Acid SCHEMBL8666991 | 0.88 | KMT2A (0.37) | MEN1KMT2ACYP3A4CYP2C9KAT6A | |
| SCHEMBL8683694 | 0.85 | KMT2A (0.41) | MEN1KMT2ACYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL8685324 | 0.83 | L3MBTL1 (0.38) | MEN1KMT2ACYP3A4CYP2C9POLB | |
| SCHEMBL8689402 | 0.83 | MEN1 (0.35) | MEN1KMT2ACYP3A4CYP2C9KAT6A | |
| Hydrochloric Acid SCHEMBL8689708 | 0.82 | MEN1 (0.35) | MEN1KMT2ACYP3A4CYP2C9KAT6A | |
| SCHEMBL8683686 | 0.81 | LMNA (0.38) | MEN1KMT2AKAT6AHTR6ALDH1A1 | |
| SCHEMBL8684161 | 0.81 | MAPT (0.40) | MEN1KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716936-A | Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders | RHONE-POULENC RORER S.A. (FR) | 1998-02-10 | — | — | US | disclosed |