Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666857 | 0.86 | KMT2A (0.38) | CYP3A4CYP2C9KAT6ALMNATSHR | |
| SCHEMBL8871034 | 0.86 | KMT2A (0.38) | CYP3A4CYP2C9KAT6ALMNATSHR | |
| Hydrochloric Acid SCHEMBL8666991 | 0.85 | KMT2A (0.37) | CYP3A4CYP2C9KAT6ALMNATSHR | |
| SCHEMBL8684409 | 0.85 | KAT6A (0.39) | KAT6AMAPK1LMNATSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8684148 | 0.84 | KAT6A (0.38) | KAT6AMAPK1LMNATSHRSMN1; SMN2 | |
| SCHEMBL8685324 | 0.81 | L3MBTL1 (0.38) | CYP3A4CYP2C9ELOVL6 | |
| SCHEMBL8689402 | 0.79 | MEN1 (0.35) | CYP3A4CYP2C9KAT6ALMNAELOVL6 | |
| SCHEMBL8684306 | 0.78 | MEN1 (0.37) | CYP3A4CYP2C9KAT6ALMNATSHR | |
| Hydrochloric Acid SCHEMBL8689708 | 0.78 | MEN1 (0.35) | CYP3A4CYP2C9KAT6ALMNAELOVL6 | |
| SCHEMBL8683694 | 0.78 | KMT2A (0.41) | CYP3A4CYP2C9LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716936-A | Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders | RHONE-POULENC RORER S.A. (FR) | 1998-02-10 | — | — | US | disclosed |