Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8684148 | 0.99 | KAT6A (0.38) | KAT6AMTNR1AMTNR1BTHRBSMN1; SMN2 | |
| SCHEMBL8666854 | 0.88 | LMNA (0.37) | LMNAPKMALDH1A1 | |
| SCHEMBL8684165 | 0.85 | CYP3A4 (0.43) | KAT6ATHRBSMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL8683844 | 0.84 | REN (0.38) | LMNAALDH1A1 | |
| SCHEMBL8683686 | 0.84 | LMNA (0.38) | KAT6ALMNAPKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL8683766 | 0.83 | REN (0.38) | LMNAALDH1A1 | |
| SCHEMBL8683956 | 0.83 | POLB (0.36) | SMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL8684040 | 0.81 | MEN1 (0.39) | SMN1; SMN2LMNATSHRPKMALDH1A1 | |
| SCHEMBL8686069 | 0.81 | RAB9A (0.38) | SMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL8666356 | 0.74 | LMNA (0.41) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716936-A | Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders | RHONE-POULENC RORER S.A. (FR) | 1998-02-10 | — | — | US | disclosed |