Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.47 |
| ▸ | CTSL | P07711 | 6/20 | 0.47 |
| ▸ | CTSB | P07858 | 5/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681567 | 0.84 | CTSB (0.51) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL7266686 | 0.80 | CTSB (0.52) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL7280270 | 0.76 | CTSB (0.55) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL8759915 | 0.76 | CTSB (0.55) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL8759866 | 0.75 | CTSB (0.54) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL7270921 | 0.75 | CTSB (0.54) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL7293547 | 0.75 | CTSB (0.54) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL7270917 | 0.75 | CTSB (0.54) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL7271139 | 0.73 | CTSL (0.56) | CTSSCTSLCTSBCTSKCASP1 | |
| SCHEMBL7271134 | 0.73 | CTSL (0.56) | CTSSCTSLCTSBCTSKCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750696-A | HYPOTENSIVE AGENTS | JAPAN TOBACCO INC. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0656356-A1 | DIOXACYCLOALKANE COMPOUND WITH RENIN-INHIBITING ACTIVITY | JAPAN TOBACCO INC. (JP) | 1995-06-07 | — | — | EP | disclosed |