Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | REN | P00797 | 8/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 3/20 | 0.44 |
| ▸ | PGA5 | P0DJD9 | 3/20 | 0.44 |
| ▸ | CTSE | P14091 | 3/20 | 0.44 |
| ▸ | PGC | P20142 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266686 | 0.87 | CTSB (0.52) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL7293547 | 0.87 | CTSB (0.54) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL7270917 | 0.87 | CTSB (0.54) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL7270921 | 0.87 | CTSB (0.54) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL8759866 | 0.87 | CTSB (0.54) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL8684410 | 0.84 | CTSS (0.47) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL9312452 | 0.83 | CTSL (0.52) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL9312089 | 0.83 | CTSL (0.52) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL8759915 | 0.83 | CTSB (0.55) | CTSBCTSLCTSSCTSKREN | |
| SCHEMBL7280270 | 0.81 | CTSB (0.55) | CTSBCTSLCTSSCTSKCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750696-A | HYPOTENSIVE AGENTS | JAPAN TOBACCO INC. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0656356-A1 | DIOXACYCLOALKANE COMPOUND WITH RENIN-INHIBITING ACTIVITY | JAPAN TOBACCO INC. (JP) | 1995-06-07 | — | — | EP | disclosed |