Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288802 | 0.78 | SLC22A12 (0.59) | SLC22A12ABHD6TUBB4ATUBBTUBA3C | |
| SCHEMBL397314 | 0.77 | NOTUM (0.69) | SLC22A12ABHD6TUBB4ATUBBTUBA3C | |
| SCHEMBL30021086 | 0.77 | NOTUM (0.69) | SLC22A12ABHD6TUBB4ATUBBTUBA3C | |
| SCHEMBL2163363 | 0.75 | SIGMAR1 (0.61) | NOTUMMEN1NPC1KMT2A | |
| SCHEMBL23064005 | 0.74 | SLC22A12 (0.56) | SLC22A12ABHD6TUBB4ATUBBTUBA3C | |
| SCHEMBL3023754 | 0.74 | SIRT2 (0.52) | NPC1KMT2A | |
| SCHEMBL18921803 | 0.73 | ABHD6 (0.64) | SLC22A12ABHD6TUBB4ATUBBTUBA3C | |
| SCHEMBL18763042 | 0.73 | SLC22A12 (0.58) | SLC22A12ABHD6TUBB4ATUBBTUBA3C | |
| SCHEMBL2083808 | 0.73 | ABHD6 (0.64) | SLC22A12ABHD6TUBB4ATUBBTUBA3C | |
| SCHEMBL20424481 | 0.73 | TSHR (0.63) | SLC22A12ABHD6TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705515-A | HAVING REDUCED SIDE EFFECTS | MERCK & CO., INC. (US) | 1998-01-06 | — | — | US | disclosed |