Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690703 | 0.87 | MAPT (0.60) | TDP1L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL8690312 | 0.84 | HRH3 (0.58) | L3MBTL1MAPTALDH1A1LMNAHRH3 | |
| SCHEMBL7804458 | 0.82 | PKM (0.53) | TDP1L3MBTL1TBXAS1ALDH1A1LMNA | |
| SCHEMBL8685448 | 0.79 | CYP1A2 (0.48) | MAPTALDH1A1LMNAHRH3CYP1A2 | |
| SCHEMBL8685427 | 0.79 | GAA (0.56) | L3MBTL1MAPTALDH1A1LMNAHRH3 | |
| SCHEMBL6701399 | 0.79 | TDP1 (0.74) | TDP1L3MBTL1TBXAS1MAPTALDH1A1 | |
| SCHEMBL2469647 | 0.77 | NPC1 (0.61) | L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL4642292 | 0.77 | LMNA (0.50) | L3MBTL1TBXAS1MAPTALDH1A1LMNA | |
| SCHEMBL9368395 | 0.76 | NAMPT (0.45) | TBXAS1MAPTALDH1A1LMNA | |
| SCHEMBL8690250 | 0.76 | HRH3 (0.48) | MAPTALDH1A1LMNAKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |