Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685265 | 0.87 | TDP1 (0.51) | MAPTALDH1A1TDP1L3MBTL1CA1 | |
| SCHEMBL8690312 | 0.86 | HRH3 (0.58) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL7804458 | 0.85 | PKM (0.53) | KDM4EALDH1A1TDP1L3MBTL1HTT | |
| Hydrochloric Acid SCHEMBL8454963 | 0.82 | ALDH1A1 (0.57) | MAPTKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4642678 | 0.81 | CYP4A11 (0.58) | MAPTKDM4EALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL8685427 | 0.81 | GAA (0.56) | MAPTKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8690250 | 0.81 | HRH3 (0.48) | MAPTALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL31177818 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1NPC1NAMPT | |
| SCHEMBL6746541 | 0.79 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1RAB9ATDP1 | |
| SCHEMBL8685448 | 0.79 | CYP1A2 (0.48) | MAPTALDH1A1SMN1; SMN2LMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |