Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438871 | 0.85 | CTSK (0.57) | CTSKACECTSSCTSLCTSB | |
| SCHEMBL9439069 | 0.82 | MMP9 (0.48) | CTSK | |
| SCHEMBL744269 | 0.82 | ATM (0.57) | CTSKATMACECTSSCTSL | |
| SCHEMBL7407045 | 0.82 | ATM (0.57) | CTSKATMACECTSSCTSL | |
| SCHEMBL9439279 | 0.82 | ATM (0.57) | CTSKATMACECTSSCTSL | |
| SCHEMBL7346811 | 0.82 | ATM (0.57) | CTSKATMACECTSSCTSL | |
| SCHEMBL7316279 | 0.82 | ATM (0.57) | CTSKATMACECTSSCTSL | |
| SCHEMBL9538641 | 0.79 | CTSK (0.59) | CTSKCTSS | |
| SCHEMBL7309827 | 0.79 | ATM (0.54) | CTSKATMACECTSSCTSL | |
| SCHEMBL1150914 | 0.79 | KLK5 (0.58) | CTSKATMACECTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847125-A | Amino acid derivatives with anticholecystokinin activity | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |
| EP-0625141-B1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY | BLACK JAMES FOUNDATION (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0625141-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY. | BLACK JAMES FOUNDATION (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993014066-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |