Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016246 | 0.93 | ELANE (0.62) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL2350995 | 0.84 | LMNA (0.53) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL777803 | 0.83 | ELANE (0.62) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL9081470 | 0.83 | LMNA (0.61) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL10585377 | 0.82 | ELANE (0.59) | LMNAPOLBELANENPC1RAB9A | |
| SCHEMBL269329 | 0.82 | LMNA (0.80) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL8308364 | 0.81 | LMNA (0.50) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL68678 | 0.81 | LMNA (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL95879 | 0.81 | LMNA (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL95878 | 0.81 | LMNA (0.59) | LMNAMAPTPOLBPKMELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264013-A | Preparation method of (1-arylmethyl-3-aryl-1-trifluoromethyl propyl) aromatic compound | 南京工业大学 | 2025-01-07 | — | — | CN | claimed |
| CN-115215841-B | Pyridinium-coumarin derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2024-01-23 | — | — | CN | claimed |
| CN-114031614-B | Fluorescent probe for double-organelle imaging, cell viability assessment and photodynamic cancer cell ablation, and preparation and application thereof | 吉林化工学院 | 2023-10-20 | — | — | CN | claimed |
| CN-116178414-A | Carboxylesterase fluorescent probe, preparation method and application thereof | 温州大学 | 2023-05-30 | — | — | CN | claimed |
| CN-115215841-A | Pyridinium-coumarin derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2022-10-21 | — | — | CN | claimed |
| CN-114031614-A | Fluorescent probe for double-organelle imaging, cell viability evaluation and photodynamic cancer cell ablation, preparation and application | 吉林化工学院 | 2022-02-11 | — | — | CN | claimed |
| US-4841009-A | Substantially linear monomeric composition and liquid crystal polymeric compositions derived therefrom | AMOCO CORPORATION (US) | 1989-06-20 | — | — | US | claimed |
| US-20260109674-A1 | ALLOSTERIC MODULATION OF MUSCARINIC ACETYLCHOLINE RECEPTOR EFFICACY | THE UNIVERSITY OF TOLEDO (US) | 2026-04-23 | — | — | US | disclosed |
| US-20250064844-A1 | N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO | EMORY UNIVERSITY | 2025-02-27 | — | — | US | disclosed |
| CN-119264013-A | Preparation method of (1-arylmethyl-3-aryl-1-trifluoromethyl propyl) aromatic compound | 南京工业大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-119198652-A | Method for ultra-sensitively detecting biodegradable microplastic and application thereof | 海南大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-119044129-A | Method for rapidly detecting biodegradable microplastic and application thereof | 海南省检验检测研究院 | 2024-11-29 | — | — | CN | disclosed |
| US-12129221-B2 | Difluoro phenyl amide RIP1 inhibitor | SIRONAX LTD (KY) | 2024-10-29 | — | — | US | disclosed |
| EP-0004727-B1 | BLOOD PLATELET AGGREGATION INHIBITORY PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-12 | — | — | EP | disclosed |
| EP-0028906-A1 | 1'-Substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones, processes for their manufacture and pharmaceutical compositions thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-05-20 | — | — | EP | disclosed |
| EP-0025496-A1 | Maytansinoids, their production and therapeutic compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-03-25 | — | — | EP | disclosed |
| EP-0024348-A1 | Substituted 6-Phenethyl-and phenylethenyl-3,4,5,6-tetrahydro-4-hydroxytetraydropyran-2-ones in the4-R trans stereoisomeric forms and the corresponding dihydroxy acids, process for preparing and pharmaceutical composition comprising them | MERCK & CO. INC. (US) | 1981-03-04 | — | — | EP | disclosed |
| EP-0004727-A2 | Blood platelet aggregation inhibitory pyridine derivatives, pharmaceutical compositions thereof, and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-10-17 | — | — | EP | disclosed |
| US-4119775-A | ANTIBACTERIAL | RICHARDSON-MERRELL INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-3989687-A | ANTIBACTERIAL | RICHARDSON-MERRELL INC. (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109674-A1 | ALLOSTERIC MODULATION OF MUSCARINIC ACETYLCHOLINE RECEPTOR EFFICACY | CHRM5, CHRM3, CHRNA3 | LMNA 4781/4885MAPT 621/4885POLB 4011/4885 |
| US-20250064844-A1 | N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO | TYMP, MTAP, DCTD | LMNA 1252/4885MAPT 4074/4885POLB 276/4885 |
| US-12129221-B2 | Difluoro phenyl amide RIP1 inhibitor | RIPK1, RIPK3, RIPK4 | LMNA 2445/4885MAPT 3429/4885POLB 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.