Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687830 | 0.89 | TACR1 (0.45) | TACR1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL8692541 | 0.88 | C5AR1 (0.41) | TACR1KMT2AMEN1MAPTTRPV1 | |
| SCHEMBL8687131 | 0.86 | TACR1 (0.53) | TACR1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL8687213 | 0.73 | TACR1 (0.49) | TACR1KMT2AMEN1MAPT | |
| SCHEMBL8687249 | 0.71 | ESRRA (0.45) | — | |
| SCHEMBL8687690 | 0.65 | MEN1 (0.40) | TACR1DRD2DRD4DRD3SOS1 | |
| SCHEMBL8811858 | 0.64 | PPARG (0.42) | MAPT | |
| SCHEMBL31255159 | 0.64 | GRM5 (0.46) | KMT2AMEN1NPSR1 | |
| SCHEMBL8686712 | 0.64 | TACR1 (0.40) | TACR1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8688100 | 0.63 | ESRRA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |