Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688100 | 0.85 | ESRRA (0.44) | NLRP3PIM1PTPN1CGASAKR1B1 | |
| SCHEMBL8687825 | 0.78 | PIM1 (0.49) | NLRP3PIM1PTPN1HTT | |
| SCHEMBL8686691 | 0.73 | AKR1B1 (0.43) | PTPN1CGASAKR1B1MAPTHTT | |
| SCHEMBL5787549 | 0.73 | NLRP3 (0.64) | NLRP3PIM1PTPN1MAPTPPARG | |
| SCHEMBL3277107 | 0.73 | AMY1A (0.61) | NLRP3PIM1PTPN1MAPTPPARG | |
| SCHEMBL5787551 | 0.73 | NLRP3 (0.64) | NLRP3PIM1PTPN1MAPTPPARG | |
| SCHEMBL3277109 | 0.73 | AMY1A (0.61) | NLRP3PIM1PTPN1MAPTPPARG | |
| SCHEMBL8687249 | 0.72 | ESRRA (0.45) | NLRP3PIM1 | |
| SCHEMBL8686390 | 0.72 | AKR1B1 (0.41) | PTPN1CGASAKR1B1MAPT | |
| SCHEMBL5461877 | 0.71 | MEN1 (0.57) | NLRP3PIM1PTPN1CGASPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |