Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.42 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687249 | 0.88 | ESRRA (0.45) | ESRRAPIM1NLRP3 | |
| SCHEMBL8689993 | 0.85 | NLRP3 (0.49) | PIM1NLRP3CGASPTPN1AKR1B1 | |
| SCHEMBL8689406 | 0.77 | PIM1 (0.44) | PIM1 | |
| SCHEMBL8688260 | 0.74 | CGAS (0.41) | NLRP3CGAS | |
| SCHEMBL8687825 | 0.73 | PIM1 (0.49) | PIM1NLRP3PTPN1 | |
| SCHEMBL8692541 | 0.72 | C5AR1 (0.41) | C5AR1 | |
| SCHEMBL8686691 | 0.71 | AKR1B1 (0.43) | CGASPTPN1AKR1B1 | |
| SCHEMBL8686390 | 0.69 | AKR1B1 (0.41) | CGASPTPN1AKR1B1 | |
| SCHEMBL8813321 | 0.67 | PARP1 (0.60) | ESRRAPIM1PTPN1AKR1B1 | |
| SCHEMBL8810478 | 0.67 | PARP1 (0.60) | ESRRAPIM1PTPN1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |