Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689406 | 0.89 | PIM1 (0.44) | PIM1 | |
| SCHEMBL8688100 | 0.88 | ESRRA (0.44) | ESRRAPIM1NLRP3 | |
| SCHEMBL8687825 | 0.85 | PIM1 (0.49) | PIM1PTGS2NLRP3 | |
| SCHEMBL6235055 | 0.74 | MEN1 (0.56) | — | |
| SCHEMBL6235054 | 0.74 | MEN1 (0.56) | — | |
| SCHEMBL5470545 | 0.74 | PTPN1 (0.48) | — | |
| SCHEMBL5470542 | 0.74 | PTPN1 (0.48) | — | |
| SCHEMBL8689993 | 0.72 | NLRP3 (0.49) | PIM1NLRP3 | |
| SCHEMBL8687698 | 0.71 | TACR1 (0.49) | — | |
| SCHEMBL13780771 | 0.69 | MMP1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |