Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5061241 | 0.67 | L3MBTL1 (0.35) | KMT2ATDP1 | |
| SCHEMBL10604455 | 0.65 | BDKRB2 (0.35) | — | |
| Bicarbonate SCHEMBL4345310 | 0.65 | PPARG (0.71) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL1645706 | 0.64 | BCHE (0.36) | KMT2ATDP1 | |
| SCHEMBL28772993 | 0.64 | S1PR1 (0.41) | KMT2AKCNH2TDP1 | |
| SCHEMBL454182 | 0.64 | S1PR1 (0.41) | KMT2AKCNH2TDP1 | |
| Bicarbonate SCHEMBL3789802 | 0.63 | TERT (0.75) | TERTPTPN1PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL10592426 | 0.63 | TERT (0.75) | TERTPTPN1PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL6246658 | 0.63 | TERT (0.75) | TERTPTPN1PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL3941976 | 0.63 | TERT (0.75) | TERTPTPN1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777104-A | Cephem derivatives as anti-metastatic agents | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-07-07 | — | — | US | claimed |