Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400674 | 0.82 | EGFR (0.54) | KEAP1NFE2L2DHODHEGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL921288 | 0.80 | EGFR (0.53) | KEAP1NFE2L2DHODHEGFRALDH1A1 | |
| SCHEMBL30316868 | 0.80 | KDM4C (0.53) | TGFBR1KDM4CALDH1A1TDP1MEN1 | |
| SCHEMBL229353 | 0.80 | KDM4C (0.53) | TGFBR1KDM4CALDH1A1TDP1MEN1 | |
| Nitrous Acid SCHEMBL27969683 | 0.77 | EGFR (0.50) | KEAP1NFE2L2DHODHEGFRALDH1A1 | |
| SCHEMBL8687708 | 0.69 | NPC1 (0.48) | KEAP1NFE2L2DHODHKDM4CALDH1A1 | |
| SCHEMBL2579028 | 0.68 | ALDH1A1 (0.52) | TGFBR1KDM4CALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL31481679 | 0.68 | KEAP1 (0.55) | KEAP1NFE2L2DHODHALDH1A1TDP1 | |
| SCHEMBL921287 | 0.68 | EGFR (0.54) | DHODHEGFRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL846877 | 0.68 | EGFR (0.50) | DHODHEGFRALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710278-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1998-01-20 | — | — | US | disclosed |