Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL28372975 | 0.82 | GSK3B (0.83) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL31085461 | 0.75 | MAOA (0.57) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL10192661 | 0.74 | GSK3B (1.00) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL29366030 | 0.74 | GSK3B (1.00) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL64 | 0.74 | GSK3B (1.00) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL7771670 | 0.74 | GSK3B (1.00) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL30125197 | 0.74 | GSK3B (1.00) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL11040503 | 0.74 | GSK3B (1.00) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL698223 | 0.72 | GSK3B (0.65) | MAOAMAOBGSK3BHSD17B10ALDH1A1 | |
| Phthalimide SCHEMBL165345 | 0.72 | GSK3B (0.94) | MAOAMAOBGSK3BHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719294-A | Process for preparing N-cyclohexylthiophthalimide | BAYER AG (DE) | 1998-02-17 | — | — | US | claimed |