Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690517 | 0.84 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8692679 | 0.84 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8690519 | 0.84 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8926807 | 0.77 | CA12 (0.49) | HIF1AEPAS1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8927711 | 0.77 | CA12 (0.49) | HIF1AEPAS1ALDH1A1KDM4EKMT2A | |
| SCHEMBL6629990 | 0.68 | NPSR1 (0.39) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8689173 | 0.66 | KDM4E (0.30) | ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL8692166 | 0.66 | KDM4E (0.30) | ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL6629994 | 0.63 | ALDH1A1 (0.41) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8692709 | 0.63 | ALDH1A1 (0.55) | HIF1AEPAS1ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843990-A | Pyran-chromenone compounds, their synthesis and anti-HIV activity | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |