Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690519 | 1.00 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8690517 | 1.00 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8689176 | 0.84 | HIF1A (0.35) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL6629990 | 0.73 | NPSR1 (0.39) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8927758 | 0.72 | ALDH1A1 (0.53) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8927755 | 0.72 | ALDH1A1 (0.53) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL6629994 | 0.68 | ALDH1A1 (0.41) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL6631879 | 0.68 | KDM4E (0.47) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8692709 | 0.66 | ALDH1A1 (0.55) | HIF1AEPAS1ALDH1A1HTTKDM4E | |
| SCHEMBL8689922 | 0.66 | ALDH1A1 (0.55) | HIF1AEPAS1ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843990-A | Pyran-chromenone compounds, their synthesis and anti-HIV activity | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |