Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689173 | 1.00 | KDM4E (0.30) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8689176 | 0.66 | HIF1A (0.35) | KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8690517 | 0.59 | HIF1A (0.39) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8692679 | 0.59 | HIF1A (0.39) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8690519 | 0.59 | HIF1A (0.39) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7332445 | 0.55 | PPARA (0.32) | — | |
| SCHEMBL6559394 | 0.55 | KDM4E (0.51) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11435171 | 0.54 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7342222 | 0.53 | PPARA (0.34) | KDM4E | |
| SCHEMBL15781983 | 0.53 | DRD2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843990-A | Pyran-chromenone compounds, their synthesis and anti-HIV activity | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |