Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688659 | 0.89 | RAB9A (0.69) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4915540 | 0.84 | NPC1 (0.76) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8689497 | 0.82 | L3MBTL1 (0.63) | TSHRMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL20620023 | 0.82 | MAPT (0.72) | MEN1KMT2ATSHRMAPTRAB9A | |
| SCHEMBL8691155 | 0.82 | HDAC1 (0.55) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8688524 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8688542 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2ATSHRMAPTRAB9A | |
| SCHEMBL8689501 | 0.78 | FAAH (0.60) | MEN1KMT2AGAAALDH1A1HTT | |
| SCHEMBL8693551 | 0.78 | RAB9A (0.54) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7142241 | 0.77 | TSHR (0.70) | MEN1KMT2ATSHRMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741926-A | ANTIDIABETIC AGENT | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997030019-A1 | ANILINE DERIVATIVES HAVING ANTIHYPERGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | disclosed |