Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690536 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL8690529 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BF2PRSS1F10 | |
| SCHEMBL7274876 | 0.82 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL5820899 | 0.79 | ITGB3 (0.67) | ITGB3ITGA2B | |
| SCHEMBL8648337 | 0.78 | ITGB3 (0.65) | ITGB3ITGA2BF2PRSS1F10 | |
| SCHEMBL8643931 | 0.72 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL6099288 | 0.72 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL8379225 | 0.72 | ITGB3 (0.48) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL8379209 | 0.72 | ITGB3 (0.48) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL8020868 | 0.70 | ITGB3 (0.75) | ITGB3ITGA2BF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747522-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5670515-A | TREATMENT OF THROMBOSIS, STROKE, CARDIAC INFARCT, INFLAMMATION, AND ARTERIOSCLEROSIS; ANTITUMOR AGENTS, WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1997-09-23 | — | — | US | disclosed |