Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 2/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31497277 | 0.79 | NCF1 (0.55) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1592724 | 0.79 | NCF1 (0.55) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5210572 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1GAAPOLBMEN1 | |
| SCHEMBL11428344 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1GAAPOLBPDGFRB | |
| SCHEMBL12199223 | 0.74 | KDM4E (1.00) | KDM4EALDH1A1GAAPOLBPDGFRB | |
| SCHEMBL6701353 | 0.74 | KDM4E (0.70) | KDM4EALDH1A1GAAPOLBPDGFRB | |
| SCHEMBL4156930 | 0.74 | PDGFRB (0.64) | KDM4EALDH1A1GAAPOLBPDGFRB | |
| SCHEMBL30223495 | 0.74 | KDM4E (0.70) | KDM4EALDH1A1GAAPOLBPDGFRB | |
| SCHEMBL14075128 | 0.73 | RAB9A (0.55) | KDM4EALDH1A1GAAPOLBPDGFRB | |
| SCHEMBL9271690 | 0.72 | FDPS (0.49) | KDM4EALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |