Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691422 | 0.80 | CNR2 (0.37) | L3MBTL1 | |
| SCHEMBL8691288 | 0.80 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C19DRD3CA1 | |
| SCHEMBL8695687 | 0.80 | FPR1 (0.34) | GAAMAPT | |
| SCHEMBL8694551 | 0.77 | FPR1 (0.40) | — | |
| SCHEMBL8879237 | 0.73 | AGTR1 (0.39) | CYP1A2CYP2D6CYP2C19DRD3CA1 | |
| SCHEMBL27798516 | 0.73 | MAPT (0.42) | CYP1A2CYP2C19LMNAGAAMAPT | |
| SCHEMBL29956676 | 0.70 | SMN1; SMN2 (0.36) | CYP1A2CYP2C19GAAMAPTL3MBTL1 | |
| SCHEMBL8692878 | 0.70 | HTT (0.43) | LMNAL3MBTL1 | |
| SCHEMBL8693592 | 0.69 | HTT (0.42) | — | |
| SCHEMBL8690276 | 0.69 | TP53 (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |