Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696774 | 0.79 | NPC1 (0.46) | AGTR1NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8690176 | 0.73 | CYP1A2 (0.35) | L3MBTL1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL8695687 | 0.73 | FPR1 (0.34) | GAA | |
| SCHEMBL8691422 | 0.71 | CNR2 (0.37) | L3MBTL1 | |
| SCHEMBL20020325 | 0.69 | POLB (0.42) | LMNAGRM2KMT2ANR1H3 | |
| SCHEMBL8694551 | 0.69 | FPR1 (0.40) | — | |
| SCHEMBL8694594 | 0.69 | NPC1 (0.35) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8691288 | 0.68 | CYP1A2 (0.35) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8692878 | 0.67 | HTT (0.43) | SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL23400193 | 0.66 | LMNA (0.41) | LMNAKMT2ANR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650414-A | PYRAZOLOPYRIDINES OR IMIDAZOLOPYRIDINES | ROUSSEL UCLAF (FR) | 1997-07-22 | — | — | US | disclosed |