Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564276 | 0.98 | TSHR (0.43) | TSHRSHBG | |
| SCHEMBL9921747 | 0.98 | TSHR (0.43) | TSHRSHBG | |
| SCHEMBL6565925 | 0.88 | TSHR (0.37) | TSHRSHBG | |
| SCHEMBL9918276 | 0.80 | SHBG (0.43) | TSHRSHBGEPHX1CTSK | |
| SCHEMBL9918275 | 0.80 | SHBG (0.43) | TSHRSHBGEPHX1CTSK | |
| SCHEMBL5063029 | 0.78 | SHBG (0.39) | TSHRSHBGEPHX1CTSKTP53 | |
| SCHEMBL9918278 | 0.78 | TSHR (0.40) | TSHRSHBG | |
| SCHEMBL9918288 | 0.78 | TSHR (0.40) | TSHRSHBG | |
| SCHEMBL18715677 | 0.77 | EPHX1 (0.43) | TSHRSHBGEPHX1TP53 | |
| SCHEMBL24332728 | 0.76 | TSHR (0.36) | TSHRSHBGEPHX1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940005-B1 | NITRILE COMPOUND, METHOD OF PREPARATION THEREOF AND FRAGRANCE COMPOSITION COMPRISING THE NITRILE COMPOUND | KAO CORP (JP) | 2017-04-05 | — | — | EP | claimed |
| CN-104884431-B | Nitrile compound | KAO CORP. (JP) | 2016-11-30 | — | — | CN | claimed |
| US-9447362-B2 | Nitrile compound | KAO CORPORATION (JP) | 2016-09-20 | — | — | US | claimed |
| US-20150353480-A1 | NITRILE COMPOUND | KAO CORPORATION (JP) | 2015-12-10 | — | — | US | claimed |
| EP-2940005-A1 | NITRILE COMPOUND | Kao Corporation (JP) | 2015-11-04 | — | — | EP | claimed |
| CN-104884431-A | Nitrile compound | KAO CORP | 2015-09-02 | — | — | CN | claimed |
| EP-2940005-B1 | NITRILE COMPOUND, METHOD OF PREPARATION THEREOF AND FRAGRANCE COMPOSITION COMPRISING THE NITRILE COMPOUND | KAO CORP (JP) | 2017-04-05 | — | — | EP | disclosed |
| EP-2940005-B1 | NITRILE COMPOUND, METHOD OF PREPARATION THEREOF AND FRAGRANCE COMPOSITION COMPRISING THE NITRILE COMPOUND | KAO CORP (JP) | 2017-04-05 | — | — | EP | disclosed |
| CN-104884431-B | Nitrile compound | KAO CORP. (JP) | 2016-11-30 | — | — | CN | disclosed |
| US-9447362-B2 | Nitrile compound | KAO CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9447362-B2 | Nitrile compound | KAO CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9447362-B2 | Nitrile compound | KAO CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20150353480-A1 | NITRILE COMPOUND | KAO CORPORATION (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20150353480-A1 | NITRILE COMPOUND | KAO CORPORATION (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2940005-A1 | NITRILE COMPOUND | Kao Corporation (JP) | 2015-11-04 | — | — | EP | disclosed |
| EP-2940005-A1 | NITRILE COMPOUND | Kao Corporation (JP) | 2015-11-04 | — | — | EP | disclosed |
| CN-104884431-A | Nitrile compound | KAO CORP | 2015-09-02 | — | — | CN | disclosed |
| US-5739375-A | REACTING WITH DIMETHYL CARBONATE IN PRESENCE OF A BASE CONTAINING NITROGEN FOR PRODUCING AN ANTIINFLAMMATORY CHEMICAL INTERMEDIATE | BASF AKTIENGELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0671379-B1 | Process for the methylation of organic compounds | BASF AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| EP-0671379-A1 | Process for the methylation of organic compounds | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353480-A1 | NITRILE COMPOUND | NOS1, NOS2, NOS3 | TSHR 4223/4885SHBG 1697/4885EPHX1 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.