Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820963 | 0.87 | CASP6 (0.58) | KMT2APOLBALDH1A1TDP1GAA | |
| SCHEMBL13675023 | 0.87 | KMT2A (0.46) | KMT2APOLBALDH1A1TDP1GAA | |
| SCHEMBL8690346 | 0.84 | HTT (0.47) | KMT2APOLBALDH1A1TDP1GAA | |
| SCHEMBL4480492 | 0.79 | CYP2C9 (0.53) | KMT2AALDH1A1GAARECQLMEN1 | |
| SCHEMBL9787566 | 0.79 | CA12 (0.46) | KMT2APOLBALDH1A1TDP1GAA | |
| SCHEMBL8693647 | 0.77 | KMT2A (0.49) | KMT2APOLBALDH1A1TDP1GAA | |
| SCHEMBL9476254 | 0.77 | KDM4E (0.50) | KMT2APOLBALDH1A1TDP1GAA | |
| SCHEMBL26036680 | 0.77 | MAOB (0.50) | KMT2APOLBALDH1A1TDP1GAA | |
| SCHEMBL9299723 | 0.77 | TSHR (0.51) | KMT2APOLBALDH1A1GAAMAPT | |
| SCHEMBL19355167 | 0.77 | ALDH1A1 (0.49) | KMT2APOLBALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598418-B2 | Naphthalene-1-(sulfonamide or carboxamide) derivatives; e.g. N-Benzyl-5-{[(4-methylphenyl)sulfonyl]oxy}naphthalene-1-sulfonamide; protein kinase inhibitors sensitize cancer cells to radiotherapy or anticancer agents; side effect reduction | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-7598418-B2 | Naphthalene-1-(sulfonamide or carboxamide) derivatives; e.g. N-Benzyl-5-{[(4-methylphenyl)sulfonyl]oxy}naphthalene-1-sulfonamide; protein kinase inhibitors sensitize cancer cells to radiotherapy or anticancer agents; side effect reduction | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20050215645-A1 | Amide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2005-09-29 | — | — | US | disclosed |
| US-5707985-A | Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators | TANABE SEIYAKU CO. LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| WO-1996040641-A1 | SULFONAMIDE DERIVATIVES AS CELL ADHESION MODULATORS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-19 | — | — | WO | disclosed |
| EP-0150319-B1 | COLOUR-PHOTOGRAPHIC RECORDING MATERIAL WITH A BLUE-GREEN DYE RELEASING COMPOUND, THE COLOUR IMAGE OBTAINED BY MEANS OF THIS DYE AND THE DYE ITSELF | Agfa-Gevaert AG (DE) | 1987-07-01 | — | — | EP | disclosed |
| EP-0132577-B1 | COLOUR-PHOTOGRAPHIC RECORDING MATERIAL WITH A DYE RELEASER FOR BLUE-GREEN DYESTUFFS, A COLOUR IMAGE OBTAINED WITH THESE DYESTUFFS AND THE DYESTUFFS THEMSELVES | Agfa-Gevaert AG (DE) | 1986-11-26 | — | — | EP | disclosed |
| US-4579805-A | DIFFUSION TRANSFER | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1986-04-01 | — | — | US | disclosed |
| EP-0150319-A2 | Colour-photographic recording material with a blue-green dye releasing compound, the colour image obtained by means of this dye and the dye itself | Agfa-Gevaert AG (DE) | 1985-08-07 | — | — | EP | disclosed |
| US-4524124-A | PHOTOSTABLE CYAN IMAGE DYES FOR DYE DIFFUSION TRANSFER | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-06-18 | — | — | US | disclosed |
| EP-0132577-A1 | Colour-photographic recording material with a dye releaser for blue-green dyestuffs, a colour image obtained with these dyestuffs and the dyestuffs themselves | Agfa-Gevaert AG (DE) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215645-A1 | Amide derivatives | OGG1, HDAC1, BCL2A1 | KMT2A 1012/4885POLB 296/4885ALDH1A1 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.