Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686247 | 0.82 | CCKBR (0.50) | MMP13ALDH1A1MMP1MMP7ACE | |
| SCHEMBL8388664 | 0.81 | SLC1A3 (0.60) | MMP13ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8388668 | 0.81 | SLC1A3 (0.60) | MMP13ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8685939 | 0.81 | CCKBR (0.54) | MMP13ALDH1A1MMP1MMP7ACE | |
| SCHEMBL8684777 | 0.81 | ALDH1A1 (0.48) | MMP13MMP3ALDH1A1MMP1MMP7 | |
| SCHEMBL8690382 | 0.81 | CCKBR (0.54) | MMP13ALDH1A1MMP1MMP7ACE | |
| SCHEMBL8717107 | 0.79 | GAA (0.45) | MMP13ALDH1A1MMP1MMP7ACE | |
| SCHEMBL8684060 | 0.79 | F2 (0.48) | MMP13ALDH1A1MMP1MMP7ACE | |
| SCHEMBL8719933 | 0.78 | CCKBR (0.45) | ALDH1A1F2GAA | |
| SCHEMBL8716958 | 0.78 | CCKBR (0.45) | ALDH1A1F2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |