Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.54 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563776 | 0.84 | ATM (0.80) | ATMKLKB1ANPEPL3MBTL1PSMB5 | |
| SCHEMBL8690683 | 0.79 | CTSL (0.64) | PSMB5PSMB1PSMB2POLB | |
| SCHEMBL12149993 | 0.75 | POLB (0.63) | ATML3MBTL1TSHRPOLBALDH1A1 | |
| SCHEMBL11758374 | 0.75 | TACR1 (0.64) | ALDH1A1 | |
| SCHEMBL11759813 | 0.75 | TACR1 (0.64) | ALDH1A1 | |
| SCHEMBL10493865 | 0.74 | ATM (1.00) | ATMANPEPL3MBTL1PSMB5TSHR | |
| SCHEMBL2561481 | 0.74 | ATM (1.00) | ATMANPEPL3MBTL1PSMB5TSHR | |
| SCHEMBL27487292 | 0.74 | ALDH1A1 (0.56) | ATMPOLBALDH1A1 | |
| SCHEMBL27487291 | 0.74 | ALDH1A1 (0.56) | ATMPOLBALDH1A1 | |
| SCHEMBL9508615 | 0.73 | POLB (0.66) | ATMKLKB1ANPEPL3MBTL1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |