Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.64 |
| ▸ | CTSB | P07858 | 3/20 | 0.64 |
| ▸ | CTSS | P25774 | 8/20 | 0.61 |
| ▸ | MMP12 | P39900 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946200 | 0.80 | CTSS (0.69) | CTSLCTSBCTSSPSMB11PSMA7 | |
| SCHEMBL14491127 | 0.80 | CTSS (0.69) | CTSLCTSBCTSSPSMB11PSMA7 | |
| SCHEMBL5181737 | 0.80 | CTSS (0.69) | CTSLCTSBCTSSPSMB11PSMA7 | |
| SCHEMBL8690667 | 0.79 | ATM (0.58) | POLBPSMB1PSMB5PSMB2 | |
| SCHEMBL6448550 | 0.78 | CTSS (0.67) | CTSLCTSBCTSS | |
| SCHEMBL7268468 | 0.78 | POLB (0.76) | CTSLCTSBCTSSPOLBGFER | |
| SCHEMBL7268474 | 0.78 | POLB (0.76) | CTSLCTSBCTSSPOLBGFER | |
| SCHEMBL7031241 | 0.77 | CTSL (0.77) | CTSLCTSBCTSSTACR2 | |
| SCHEMBL7031248 | 0.77 | CTSL (0.77) | CTSLCTSBCTSSTACR2 | |
| SCHEMBL7026935 | 0.77 | CTSL (0.77) | CTSLCTSBCTSSTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | claimed |
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |