SCHEMBL29946200

SCHEMBL29946200

O=C(CF)C(CCc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)N1CCOCC1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSS P25774 12/20 0.69
CTSL P07711 8/20 0.65
CTSB P07858 7/20 0.61
CTSK P43235 3/20 0.51
CTSH P09668 1/20 0.50
CTSC P53634 1/20 0.50
PSMB11 A5LHX3 1/20 0.49
PSMA7 O14818 1/20 0.49
PSMB1 P20618 1/20 0.49
PSMA1 P25786 1/20 0.49
PSMA2 P25787 1/20 0.49
PSMA3 P25788 1/20 0.49
PSMA4 P25789 1/20 0.49
PSMB8 P28062 1/20 0.49
PSMB9 P28065 1/20 0.49
PSMA5 P28066 1/20 0.49
PSMB4 P28070 1/20 0.49
PSMB6 P28072 1/20 0.49
PSMB5 P28074 1/20 0.49
PSMB10 P40306 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14491127 1.00 CTSS (0.69) CTSSCTSLCTSBCTSKCTSH
SCHEMBL5181737 1.00 CTSS (0.69) CTSSCTSLCTSBCTSKCTSH
SCHEMBL6448550 0.90 CTSS (0.67) CTSSCTSLCTSBCTSKCTSH
SCHEMBL30747838 0.86 CTSS (0.68) CTSSCTSLCTSBCTSKCTSH
SCHEMBL7026935 0.82 CTSL (0.77) CTSSCTSLCTSBCTSKCTSH
SCHEMBL7031241 0.82 CTSL (0.77) CTSSCTSLCTSBCTSKCTSH
SCHEMBL7031248 0.82 CTSL (0.77) CTSSCTSLCTSBCTSKCTSH
SCHEMBL7411039 0.82 CTSS (0.69) CTSSCTSLCTSBCTSKCTSH
SCHEMBL7411052 0.82 CTSS (0.69) CTSSCTSLCTSBCTSKCTSH
SCHEMBL7411037 0.82 CTSS (0.69) CTSSCTSLCTSBCTSKCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CTSS 396/4885CTSL 371/4885CTSB 300/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 CTSS 396/4885CTSL 371/4885CTSB 300/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 CTSS 396/4885CTSL 371/4885CTSB 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.