Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 17/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 14/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689717 | 0.82 | MAOA (0.47) | CHEK1CDK4 | |
| SCHEMBL8006987 | 0.70 | TDP2 (0.48) | WEE1CHEK1 | |
| SCHEMBL5829446 | 0.68 | WEE1 (1.00) | WEE1CHEK1ROCK2MEN1PRKD3 | |
| SCHEMBL31061050 | 0.68 | WEE1 (1.00) | WEE1CHEK1ROCK2MEN1PRKD3 | |
| SCHEMBL7912408 | 0.66 | CYP1A2 (0.66) | TDP1 | |
| SCHEMBL8694298 | 0.66 | GNRHR (0.43) | — | |
| SCHEMBL5828716 | 0.65 | CHEK1 (1.00) | WEE1CHEK1ROCK2MEN1PRKD3 | |
| SCHEMBL7905523 | 0.65 | GAA (0.54) | MEN1KMT2A | |
| SCHEMBL8692753 | 0.65 | GNRHR (0.42) | — | |
| SCHEMBL8692748 | 0.65 | GNRHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756507-A | TREATING SEX HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |