Potassium Ion — predicted protein targets

Known targets — ChEMBL curated mechanism

AGTR1 DHFR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GART NR3C2 PBP2X PTGS1 PTGS2 VKORC1 bla blaT-3 blaT-4 blaT-5 blaT-6 dacA dacB dacC folA ftsI mrcA mrcB mrdA pbp1a pbp1b pbp2a pbp2b pbp3 pol thyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	3/20	0.34

▸	HPGD	P15428	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL867420	0.97	TSHR (0.34)	TSHRHPGD
Potassium Ion SCHEMBL868651	0.87	TSHR (0.36)	TSHRHPGD
SCHEMBL5956774	0.83	TSHR (0.36)	TSHRHPGD
Potassium Ion SCHEMBL28968181	0.82	TSHR (0.38)	TSHRHPGD
SCHEMBL561301	0.80	TSHR (0.45)	TSHRHPGD
SCHEMBL28658770	0.79	TSHR (0.38)	TSHRHPGD
SCHEMBL28654187	0.79	TSHR (0.38)	TSHRHPGD
Potassium Ion SCHEMBL31601056	0.76	TSHR (0.36)	TSHRHPGD
SCHEMBL3164711	0.74	TSHR (0.41)	TSHRHPGD
SCHEMBL7192136	0.73	TSHR (0.39)	TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20120077718-A1	COPOLYMER AND PREPARATION METHOD AND APPLICATION THEREOF	SINOPEC RESEARCH INSTITUTE OF PETROLEUM ENGINEERING (CN)	2012-03-29	—	—	US	disclosed