Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Cyclohexylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL28990230 | 0.96 | ALDH1A1 (0.38) | ALDH1A1MMP8MMP1MMP2SMYD3 | |
| Cyclohexylamine SCHEMBL643896 | 0.87 | SMYD3 (0.37) | ALDH1A1MMP8MMP1MMP2SMYD3 | |
| Cyclohexylamine SCHEMBL25275647 | 0.87 | APP (0.38) | EPHX1NAAAENPP2 | |
| Cyclohexylamine SCHEMBL31155310 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MMP8MMP1MMP2SMYD3 | |
| SCHEMBL520280 | 0.85 | MMP8 (0.42) | ALDH1A1MMP8MMP1MMP2SMYD3 | |
| Cyclooctanamine SCHEMBL521739 | 0.85 | MMP8 (0.42) | ALDH1A1MMP8MMP1MMP2SMYD3 | |
| Cyclohexylamine SCHEMBL27416385 | 0.85 | MMP8 (0.42) | ALDH1A1MMP8MMP1MMP2SMYD3 | |
| Cyclohexylamine SCHEMBL3501943 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MMP8MMP1EPHX1CA1 | |
| Cyclohexylamine SCHEMBL27744924 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MMP8MMP1EPHX1CA1 | |
| Cyclohexylamine SCHEMBL28534696 | 0.84 | APP (0.39) | EPHX1NAAAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118348259-A | Application of reagent for detecting CK-8 protein level in preparation of intestinal mucosa necrosis diagnosis product | 湖南永和阳光生物科技股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-117965667-A | Method for preparing polypeptide by cutting fusion protein | 陕西普罗安蒂生物科技发展有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117074689-A | Factor B detection kit | 山东博科生物产业有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-116253424-A | Method for efficiently degrading fluoroquinolone antibiotics by using natural mineral materials | 南京大学 | 2023-06-13 | — | — | CN | claimed |
| CN-116139105-A | Protein nucleic acid nano-particle and preparation method thereof | 中国科学院生物物理研究所 | 2023-05-23 | — | — | CN | claimed |
| CN-114778824-A | Novel immunoturbidimetric kit for detecting procalcitonin | 安徽环球基因科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114280288-A | Novel immunoturbidimetric kit for detecting procalcitonin | 安徽环球基因科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-114031718-A | Solvent type dispersion resin for high solid content coating and preparation method thereof | 上海金仕迈树脂有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-110670050-B | Chemical copper plating activating solution and preparation method thereof | 深圳市松柏实业发展有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-113172199-A | Preparation method of novel ammonia-free curing type casting precoated sand | 广西兰科资源再生利用有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-109852221-B | Low-VOC high-performance double-component waterborne polyurethane wood coating and preparation method thereof | 中海油常州涂料化工研究院有限公司 | 2021-07-13 | — | — | CN | claimed |
| CN-105829376-B | Method for producing water-emulsifiable polyurethane acrylates | 巴斯夫欧洲公司 | 2020-03-27 | — | — | CN | claimed |
| CN-110670050-A | Chemical copper plating activating solution and preparation method thereof | 深圳市松柏实业发展有限公司 | 2020-01-10 | — | — | CN | claimed |
| EP-1957555-B1 | RADIATION-CURABLE WATER-EMULSIFIABLE POLYISOCYANATES | BASF SE (DE) | 2019-06-19 | — | — | EP | claimed |
| US-10294392-B2 | Process for preparing water-emulsifiable polyurethane acrylates | BASF SE (DE) | 2019-05-21 | — | — | US | claimed |
| CN-108912067-A | A kind of 2,3,5 triphenyltetrazolium chlorid preparation method | 湖南恒泰化工有限公司 | 2018-11-30 | — | — | CN | claimed |
| EP-3058008-B1 | USE OF WATER-EMULSIFIABLE POLYURETHANE ACRYLATES | BASF SE (DE) | 2017-06-14 | — | — | EP | claimed |
| US-20160251543-A1 | PROCESS FOR PREPARING WATER-EMULSIFIABLE POLYURETHANE ACRYLATES | BASF SE (DE) | 2016-09-01 | — | — | US | claimed |
| US-7943682-B2 | Radiation-curable water-emulsifiable polyisocyanates | BASF AKTIENGESELLSCHAFT (DE) | 2011-05-17 | — | — | US | claimed |
| US-20080300338-A1 | Radiation-Curable Water-Emulsifiable Polyisocyanates | BASF SE (DE) | 2008-12-04 | — | — | US | claimed |